.page-section-heading{padding:25px 0 20px 0}
.panel-body .page-section-heading, .additional-section .page-section-heading, .additional-page .page-section-heading{padding: 31px 0 20px 0}
.mechanism-of-action .container.middle-content > div:nth-last-of-type(3), .clinical-pharmacology .container.middle-content > div:nth-last-of-type(3), 
.differences-in-platelet-inhibitors .container.middle-content > div:nth-last-of-type(3),
.differences-in-platelet-inhibitors .container.middle-content > div:nth-last-of-type(4){max-width:100%;padding:0;width:100%;padding:0}
.component-section.additional-page{border-top:8px solid rgba(214,214,214,0.8);margin-top:20px}
.clinical-pharmacology .component-section.additional-page{margin-top:0}
.mechanism-of-action .footnote-section, .differences-in-platelet-inhibitors .footnote-section{border-top:0;margin:0}
/*mechanism-of-action starts*/
.adp-content-img .column-1, .adp-content-img .column-2{padding-top:30px}
.adp-content-img{padding-bottom:30px}
.adp-content-img .column-2 p{padding-bottom:28px}
.mechanism-of-action .visual-col{padding-top:125px}
.visual-col .column-2 .about-brilnta-col{background-color:rgba(97,17,106,0.8)}
.mechanism-of-action .visual-col .column-1 .about-brilnta-col, .visual-col .column-3 .about-brilnta-col{background-color:rgba(152,112,161,0.9)}
.mechanism-of-action .visual-col .column-2 .orange{padding:0 40px 10px 40px}
/*.mechanism-of-action .visual-col .column-1 .text,
.mechanism-of-action .visual-col .column-3 .text{position:relative;top:120px}
.mechanism-of-action .visual-col .column-2 .text{position:relative;top:100px}*/
ol.list-view{padding-left:17px}
.underline{text-decoration:underline}
.about-bri-img{margin:0 auto;width:100%;max-width:400px} 
.mechanism-of-action .adhession{width:170px;margin:0 auto;display:block;margin:0 auto;position:relative;top:-85px;border:6px #9870a1 solid;border-radius:50%}
.mechanism-of-action .visual-col .column-2 .adhession{border-color:#61116a}
.activation-text{top:-70px;position:relative}
/*mechanism-of-action ends*/
/*clinical-pharmacology starts*/

.clinical-pharmacology .right-border-column-container{border-bottom:2px solid rgba(214,214,214,0.7);padding:10px 0;margin-bottom:10px}
.clinical-pharmacology .last-col{border-bottom:0;padding:0;margin:0}
.clinical-pharmacology .pharma-graph{max-width:375px;width:100%;margin:0 auto}
.clinical-pharmacology .custom-table{margin-bottom:20px}
.clinical-pharmacology .additional-section{padding-top:34px;margin-top:55px}
.clinical-pharmacology .custom-table > div p{margin:0;padding-bottom:25px}
.clinical-pharmacology .custom-table .thick-border{margin:0;}
.clinical-pharmacology .custom-table .title{text-align:center}
.clinical-pharmacology .custom-table .thick-border{padding:12px 0}
.clinical-pharmacology .additional-section .page-section-inner.container{padding:0}
.clinical-pharmacology .custom-table .thick-border{border-bottom:4px solid #ddc9e2}
.clinical-pharmacology .additional-page .list-view li{padding-left:12px}

/*clinical-pharmacology ends*/

/*differences-in-platelet-inhibitors starts*/
.differences-in-platelet-inhibitors .right-border-column-container .column-2 .text.parbase ul.list-view li,
.differences-in-platelet-inhibitors .right-border-column-container p{padding:15px 0 15px 15px}
.differences-in-platelet-inhibitors .additional-acs{border:1px solid #61116a}
.about-tables{max-width:450px;margin:0 auto}
.differences-in-platelet-inhibitors .foot-notes{margin-left:10px}
.differences-in-platelet-inhibitors .right-border-column-container .col-xs-12{padding:0}
.differences-in-platelet-inhibitors .additional-page{margin-top:38px;padding-top:40px}
.differences-in-platelet-inhibitors .additional-page .foot-notes{padding-top:18px}
.differences-in-platelet-inhibitors .foot-notes p{
    margin-bottom:10px;
    text-indent: -7px; 
}
.differences-in-platelet-inhibitors p.footnote.textIndex-0 {
    text-indent: 0px;
}
.differences-in-platelet-inhibitors .footnote.diff-platelet-int {
    text-indent: -7px;
}
sup.double-dragg{font-size:90%}
.clinical-pharmacology.stroke-indication .pharmacokinetics, 
.clinical-pharmacology.cad-indication .pharmacokinetics{display:none}

.clinical-pharmacology.stroke-indication .additional-page, 
.clinical-pharmacology.cad-indication .additional-page{margin-top:32px}
/*differences-in-platelet-inhibitors ends*/
@media screen and (max-width:768px){
  .clinical-pharmacology .banner-title{ right: -85px; }
}
@media screen and (max-width:991.5px){
    .differences-in-platelet-inhibitors.acs-indication .banner-title{ left: 70px;  top: 46%;}
.clinical-pharmacology .banner-title{ left: 115px; }
.page-section-heading{padding: 25px 0 20px 0}
    .mechanism-of-action .page-section-heading{padding:31px 0 20px 0}
    .component-section.additional-section .container, .component-section.additional-page .container{padding-left:0;padding-right:0}
.differences-in-platelet-inhibitors .banner-title{padding:0 90px}
.clinical-pharmacology .banner-title{
    padding:0 90px;
    top: 65px;
}
.mechanism-of-action .banner-title{
    padding:0 90px;
    top: 62px;
}
.mechanism-of-action .page-section-heading h2{padding-top:12px}
.mechanism-of-action .page-section-heading{padding: 10px 0 20px 0}h3.d-hide.title.text-center {font-size: 16px;line-height: normal;}
.mechanism-of-action .page-section-heading{padding-bottom:5px}
.mechanism-of-action .adp-content-img .column-1{padding-left:0;padding-right:0}
.mechanism-of-action .adp-content-img .column-2 .card-text p:nth-last-of-type(1){padding-bottom:0}
.mechanism-of-action .additional-section{margin-top:0}
.mechanism-of-action .additional-section .page-section-heading{padding-top:15px}
.mechanism-of-action .visual-col .column-1 h4, .mechanism-of-action .visual-col .column-2 h4, .mechanism-of-action .visual-col .column-3 h4{padding-bottom:10px}
.col-xs-12{float:none}
.custom-table span.text.m-adj{position:relative;top:-36px}

.mechanism-of-action .visual-col .column-1 .about-brilnta-col, .mechanism-of-action .visual-col .column-2 .about-brilnta-col,
.mechanism-of-action .visual-col .column-3 .about-brilnta-col{max-width:350px;width:100%;margin:0 auto;padding:0 5px}
.mechanism-of-action .visual-col .column-2 .about-brilnta-col{height: 332px;}
.adhession-text{position:relative;top:-50px}
.mechanism-of-action .visual-col .column-2{margin:120px auto}
.clinical-pharmacology .four-column .column2, .clinical-pharmacology .four-column .column3, 
.clinical-pharmacology .four-column .column4{max-width:400px;width:100%}
.clinical-pharmacology .custom-table .thick-border{border-bottom:0}
.clinical-pharmacology .additional-section{margin-top:26px;padding-top:26px}
.clinical-pharmacology .custom-table{margin:25px auto 35px auto}
.clinical-pharmacology .additional-page, .differences-in-platelet-inhibitors .additional-page{padding-left:10px;padding-right:10px}
.clinical-pharmacology .additional-page .page-section-heading{padding-top:34px}
.clinical-pharmacology .right-border-column-container{padding:12px 0;margin-bottom:12px}
.clinical-pharmacology .text.parbase ul.list-view li{padding-bottom:6px}
.clinical-pharmacology .isi-footer-content .text.parbase ul.list-view li{padding-bottom:0px}
.clinical-pharmacology .text.parbase ul.list-view li:nth-last-of-type(1){padding-bottom:0}
.additional-page .text.parbase ul.list-view{margin-bottom:0}
.differences-in-platelet-inhibitors .row{margin:0}
.differences-in-platelet-inhibitors .right-border-column-container .column-2 .text.parbase ul.list-view li, 
.differences-in-platelet-inhibitors .right-border-column-container p{padding:10px 0 10px 15px}
.right-border-column-container .column-2 .right-column{padding-bottom:0}
.clinical-pharmacology .text.parbase ul.list-view .pd-btm-20{padding-bottom:20px}
.clinical-pharmacology .custom-table p.bdr-tp{padding-bottom:36px} 
.clinical-pharmacology .custom-table > div p{margin:0 15px}
.clinical-pharmacology .text.parbase ul.list-view li ul.sub-list.spacing{padding-top:6px}
}
@media screen and (min-width:992px){
.component-section.additional-section .page-section-inner.container,
.component-section.additional-page .page-section-inner.container{padding-left:0;padding-right:0}

/*mechanism-of-action starts*/
.about-bri-img{max-width:600px}
.mechanism-of-action .additional-section .page-section-heading{padding-top:23px}
.mechanism-of-action .visual-col .column-1, .mechanism-of-action .visual-col .column-2,
.mechanism-of-action .visual-col .column-3{width:400px}
.mechanism-of-action .visual-col .column-1 p.card-text, .mechanism-of-action .visual-col .column-2 p.card-text,
.mechanism-of-action .visual-col .column-3 p.card-text{padding:0 10px}
.mechanism-of-action .visual-col .column-1 .about-brilnta-col, .mechanism-of-action .visual-col .column-2 .about-brilnta-col,
.mechanism-of-action .visual-col .column-3 .about-brilnta-col{max-width:370px;height:330px}
.mechanism-of-action .adhession{top:-70px}
.activation-text{top:-54px}
.mechanism-of-action .visual-col{padding-top:106px;width:1200px;margin-left:-15px}
.mechanism-of-action .visual-col .column-1 h4, .mechanism-of-action .visual-col .column-2 h4,
.mechanism-of-action .visual-col .column-3 h4{padding-bottom:10px}
.adp-content-img{padding-bottom:18px}
.adp-content-img .column-2{margin-top:50px}
/*mechanism-of-action ends*/
/*clinical-pharmacology starts*/
.clinical-pharmacology .four-column .column1{width:405px}
.clinical-pharmacology .four-column .column2, .clinical-pharmacology .four-column .column3, .clinical-pharmacology .four-column .column4{width:185px}
.clinical-pharmacology .right-border-column-container{padding-bottom:20px;margin-bottom:20px}
.clinical-pharmacology .right-border-column-container:nth-last-of-type(1){margin-bottom:14px}
.clinical-pharmacology .right-border-column-container .col-sm-3{width:16%}
.clinical-pharmacology .right-border-column-container .col-sm-9{width:84%}
.clinical-pharmacology .pharma-graph{max-width:590px;margin-bottom:30px}
.clinical-pharmacology .custom-table{margin:15px auto 33px auto}
.clinical-pharmacology .custom-table .col-right{width:370px}
.clinical-pharmacology .no-border{border-bottom:0}
.clinical-pharmacology .page-section-heading h3{padding-top:16px}
.clinical-pharmacology .custom-table .bdr-tp{border-top:6px solid #fff}
.clinical-pharmacology .custom-table .d-pB{padding-bottom:39px}
.clinical-pharmacology .custom-table .d-pB37{padding-bottom:37px}
.clinical-pharmacology .custom-table .pd-top{padding-bottom:18px}
.clinical-pharmacology .custom-table .column2 .thick-border, .clinical-pharmacology .custom-table .column3 .thick-border,
.clinical-pharmacology .custom-table .column4 .thick-border{border-color:#9871a2}
.clinical-pharmacology .custom-table .thick-border{padding:12px 0 8px 0}
.clinical-pharmacology .custom-table hr{width:970px}
.clinical-pharmacology.stroke-indication .right-border-column-container:nth-last-of-type(1), 
.clinical-pharmacology.cad-indication .right-border-column-container:nth-last-of-type(1),.clinical-pharmacology.acs-indication .right-border-column-container:nth-last-of-type(1){margin-bottom:0;padding-bottom:0}


/*clinical-pharmacology ends*/

/*differences-in-platelet-inhibitors starts*/
.differences-in-platelet-inhibitors .additional-page{margin-top:36px;padding-top:15px}
.about-tables{max-width:1130px}

.differences-in-platelet-inhibitors .page-section-heading{width:68%}
.differences-in-platelet-inhibitors .right-border-column-container .row{margin:0}
.differences-in-platelet-inhibitors .right-border-column-container .column-2 .right-column{padding-left:0}
/*differences-in-platelet-inhibitors ends*/


}
@media screen and (min-width:768px) and (max-width:991.5px){    
.differences-in-platelet-inhibitors .container.middle-content .visible-sm-inline-block{display: none !important}
.differences-in-platelet-inhibitors .container.middle-content .new-image .new-image-desktop {display: none}
.differences-in-platelet-inhibitors .container.middle-content .visible-xs-inline-block{display: inline-block !important}
.differences-in-platelet-inhibitors .container.middle-content .new-image .new-image-mobile{display: inline-block}
.differences-in-platelet-inhibitors .banner-title{max-width:300px;padding:0}
.differences-in-platelet-inhibitors.stroke-indication .banner-title,.differences-in-platelet-inhibitors.cad-indication .banner-title,.differences-in-platelet-inhibitors.acs-indication .banner-title{ left: 215px;}
}
@media screen and (min-width:991.5px) and (max-width:1200.5px){ 
    .differences-in-platelet-inhibitors .banner-title{ width: 700px;}
    .mechanism-of-action .visual-col{width:990px;margin:0 auto}
.mechanism-of-action .visual-col .column-1, .mechanism-of-action .visual-col .column-2, .mechanism-of-action .visual-col .column-3{width:330px}
.mechanism-of-action .visual-col .column-1 .about-brilnta-col, .mechanism-of-action .visual-col .column-2 .about-brilnta-col, 
.mechanism-of-action .visual-col .column-3 .about-brilnta-col{height:370px}
/*.clinical-pharmacology .banner-title{left:-80px;     max-width: 500px;}
.clinical-pharmacology.stroke-indication .banner-title,.clinical-pharmacology.cad-indication .banner-title,.clinical-pharmacology.acs-indication .banner-title{ left: 220px; }*/
.differences-in-platelet-inhibitors .banner-title{left:-75px}
.differences-in-platelet-inhibitors .about-imf{margin-left:0.7px}
}
@media screen and (max-width: 500px){
  .mechanism-of-action .banner-title{ left: 55px;}
}
@media screen and (min-width: 500px) and (max-width:767px){
    .mechanism-of-action .subpage-banner .banner-title{ 
	left: 140px !important;
    top: 85px;
}
    .subpage-banner .banner-title{left:-80px}
.differences-in-platelet-inhibitors .subpage-banner .banner-title{left: 100px;
    width: 90%;
    top: 85px;}
.differences-in-platelet-inhibitors .banner-title{ left: 100px;}
                }
@media screen and (max-width:427px){
.explore-more .explore-more-list li a.arrow-top::after{position:relative;top:-22px}
.clinical-pharmacology .banner-title {
    left: 75px;
}
        }
@media screen and (max-width:427px){
.about-bri-img .new-image-desktop{height:420px}
.differences-in-platelet-inhibitors .banner-title {
                left: 55px;     top: 51%;}
}
@media screen and (min-width:321px) and (max-width:350px){ 
    .clinical-pharmacology h2.banner-title{padding:0 80px}

}